Osteosarcoma of the ulna with pulmonary metastasis in Agapornis roseicollis
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Abstract
Osteosarcoma (OSA) is a malignant bone neoplasm of mesenchymal origin characterized by the proliferation of osteoblasts, being considered rare in birds. This paper discusses a rare occurrence of osteosarcoma in a wing with pulmonary metastasis in a Agapornis roseicollis, with a history of prostration and a drooping left wing for two days. Radiographic examination revealed findings indicative of an aggressive bone lesion in the proximal third of the left ulna, and signs of a pathological fracture in the ipsilateral radius. Additionally, a focal nodular lesion was identified in the left pulmonary field within the coelomic cavity. Cytological examination of the wing neoformation revealed signs of infiltrative, non-encapsulated malignant neoplastic proliferation of osteoblasts, consistent with a malignant mesenchymal neoplasm. Three days later, the patient died, and post-mortem and histopathological examinations of the lesions were consistent with OSA in the wing associated with pulmonary metastasis. Due to the scarcity of data regarding this theme, the present report could be useful for veterinarians.
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References
Dittmer K. E. et al., 2012. Primary bone tumors in birds: a review and description of two new cases. Avian Diseases, 56(2):422-6. doi:10.1637/9854-071911
Doolen M. 1994. Adriamycin chemotherapy in a blue-fronted Amazon with osteosarcoma. Proc Annu Conf Assoc Avian Vet, 89-91.
Filippich L. J. 2004.Tumor control in birds. Semin Avian Exotic Pet Med, 13(1):25-43. doi:10.1053/S1055-937X(03)00055-0
Fordham M et al., 2010. Intraocular osteosarcoma in an umbrella cockatoo (Cacatua alba). Vet Ophthalmol, 13 Suppl:103-8. doi:10.1111/j.1463-5224.2010.00798.x.
Hartup B. K, Steinberg H. 1996. Osteosarcoma in an American robin (Turdus migratorius). Avian Diseases, 40(4):938-40.
Hastain S. A et al., 2024. Osteosarcoma of the wing in a sulfur-crested cockatoo. Vet Clin Pathol. 53(1):111-5. doi:10.1111/vcp.13322.
Lamb S et al., 2014. Osteosarcoma of the tibiotarsus with possible pulmonary metastasis in a ring-necked dove (Streptopelia risoria). J Avian Med Surg, 28(1):50-6. doi:10.1647/2012-064.
Liu S. K, Dolensak E. P, Tappe J. P. 1982. Osteosarcoma with multiple metastases in a Panama boat-billed heron. J Am Vet Med Assoc, 181(11):1396–8.
Mayer J et al., 2009. Management of osteosarcoma in a grey goose. Proc Annu Conf Assoc Avian Vet, p. 335.
Reavill D. R. 2004. Tumors of pet birds. Vet Clin North Am Exot Anim Pract, 7(3):537–60. doi:10.1016/j.cvex.2004.04.008.
Robat C. S, Ammersbach M, Mans C. 2017. Avian oncology: diseases, diagnostics, and therapeutics. Vet Clin North Am Exot Anim Pract, 20(1):57–86. doi:10.1016/j.cvex.2016.07.009.
Ruano-Feo I et al., 2024. Undifferentiated Wing Sarcoma in a Peach-Faced Lovebird (Agapornis roseicollis). J Comp Pathol, 199:81–5. doi:10.1016/j.jcpa.2022.09.006.
Schmidt R. E, Quesenberry K. 1997. Neoplasia. In: Altman RB, editor. Avian Medicine and Surgery. Philadelphia: Saunders, p. 590–603.
Seiler G. S, Thrall D. E. 2024. Thrall’s Textbook of Veterinary Diagnostic Radiology. 8th ed. Philadelphia: Elsevier Saunders.
Szewczyk M, Lechowski R, Zabielska K. 2014. What do we know about canine osteosarcoma treatment? Review. Vet Res Commun, 39(1):61–7. doi:10.1007/s11259-014-9623-0